Tetrahydrofuran (THF)

Tetrahydrofuran (THF)

CAS 109-99-9SolventsTHF

Specifications

CAS No.
109-99-9
Melting point
-108.5°C
Boiling point
66°C

Product overview

Tetrahydrofuran (THF) is a heterocyclic organic compound with the formula (CH2)4O. Classified as a cyclic ether, it is a colorless, water-miscible organic liquid with low viscosity. THF is primarily used as a precursor to polymers and as a versatile solvent in organic synthesis, particularly for reactions involving organometallic compounds.

Key features

  • Miscible with water in all proportions - unusual for ethers
  • Excellent solvent for both polar and nonpolar compounds
  • Low viscosity for easy handling and filtration
  • Wide liquid range (-108°C to 66°C)
  • Can form explosive peroxides when exposed to air
  • Polar aprotic solvent - good for SN2 reactions
  • Compatible with most organic compounds and polymers
  • Rapid evaporation rate for fast processing.

Applications

Polymer industry
production of PTMEG for spandex fibers, polyurethanes
Organic synthesis
solvent for Grignard reactions, organolithium reactions
Pharmaceutical industry
reaction solvent, purification, crystallization
Coatings and adhesives
solvent for PVC, PVDF, and other polymers
Laboratory
universal solvent for chromatography and extraction
Chemical manufacturing
production of butanediol, gamma-butyrolactone
Resin processing
solvent for epoxy resins, vinyl polymers
Film casting
solvent for polymer film production
Histology
tissue processing and staining.
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