Chlorhexidine Diacetate

Chlorhexidine Diacetate

CAS 56-95-1Pharma intermediatesCD

Specifications

CAS No.
56-95-1
Molecular weight
625.55
Melting point
153-156°C
Boiling point
Not applicable

Appearance & character

White or almost white crystalline powder, odorless with a bitter taste. It is the diacetate salt of chlorhexidine, a cationic antimicrobial agent.

Product overview

Chlorhexidine diacetate is the diacetate salt of chlorhexidine, a cationic broad-spectrum antimicrobial agent belonging to the bis(biguanide) family. With the chemical formula C22H30Cl2N10·2(C2H4O2) and molecular weight of 625.55 g/mol, it is widely used as a disinfectant and topical anti-infective agent. Its mechanism of action involves destabilization of the outer bacterial membrane, leading to cell death. It is effective against both Gram-positive and Gram-negative bacteria, as well as some fungi and viruses. Chlorhexidine diacetate has fast and long-lasting effects with extremely low toxicity.

Key features

  • Broad-spectrum antibacterial activity against Gram-positive and Gram-negative bacteria
  • Fast-acting and long-lasting antimicrobial effects
  • Extremely low toxicity, almost not absorbed by the body
  • No irritation or allergic reactions at effective concentrations
  • Soluble in ethanol, slightly soluble in water
  • Cationic compound that binds to bacterial membranes
  • Bitter taste characteristic of chlorhexidine salts
  • Stable under proper storage conditions.

Applications

Medical and dental
mouthwash to prevent oral plaque, surgical scrubs, wound cleansing
Healthcare
skin antiseptic, catheter site care, medical device disinfection
Pharmaceutical
preservative in eye drops, topical preparations, and pharmaceutical products
Cosmetics
preservative in creams, toothpaste, deodorants, and personal care products
Veterinary
antiseptic for animal wounds and surgical procedures
Food industry
surface disinfection in food handling facilities
Household
disinfectant solutions and cleaning products
Industrial
antimicrobial agent in various industrial processes.
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