Piperine

CAS 94-62-2Pharma intermediatesPIPERC17H19NO3

Specifications

CAS No.
94-62-2
Molecular formula
C17H19NO3
Molecular weight
285.34
Melting point
129-135°C
Boiling point
Not applicable (decomposes before boiling)

Appearance & character

Light yellow crystalline powder with a characteristic pungent taste. Initially tasteless, it produces a burning sensation after a short delay. It is an alkaloid isolated from black pepper.

Product overview

Piperine is a naturally occurring alkaloid with the chemical formula C17H19NO3 and molecular weight of 285.34 g/mol. It is the principal active component of black pepper (Piper nigrum) and long pepper, responsible for their pungency. Piperine has been extensively studied for its various pharmacological properties including anti-inflammatory, analgesic, antioxidant, and bioavailability-enhancing effects. It is widely used in traditional medicine, food industry, and pharmaceutical applications.

Key features

  • Natural alkaloid extracted from black pepper
  • Exhibits pungent taste with delayed burning sensation
  • Poor water solubility but soluble in organic solvents
  • Enhances bioavailability of various compounds
  • Multiple pharmacological activities
  • TRPV1 receptor activator
  • Modulates GABAA receptors
  • Stable under normal storage conditions.

Applications

Food industry
spicy raw material, flavor enhancer, and natural preservative
Pharmaceutical industry
bioavailability enhancer, anti-inflammatory, analgesic, and antioxidant agent
Traditional medicine
treatment for various ailments including digestive disorders, inflammation, and pain
Nutraceuticals
dietary supplement ingredient for metabolic support
Cosmetics
ingredient in skincare products for its antioxidant properties
Research
biofilm research, inhibits biofilm formation of Candida albicans and Streptococcus mutans
Agricultural applications
insecticide and pesticide formulations
Veterinary medicine
digestive and respiratory health support.
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