2,4,5,6-Tetraaminopyrimidine Sulfate

2,4,5,6-Tetraaminopyrimidine Sulfate

2,4,5,6-Tetraaminopyrimidine Sulfate

CAS 5392-28-9Pharma intermediates

Specifications

CAS No.
5392-28-9
Appearance
Light yellow to ochre Crystalline Powder
Melting point
>300℃ (decomposes)
Boiling point
Not available (decomposes)

Product overview

2,4,5,6-Tetraaminopyrimidine sulfate is the sulfate salt of 2,4,5,6-tetraaminopyrimidine, appearing as a light yellow to ochre crystalline powder with a melting point above 300℃. It is a key intermediate in the production of methotrexate and other antifolate pharmaceuticals, and is also used as a precursor for hair dye couplers. in water. In acidic solutions, it is colorless, while in basic solutions, it turns pink to purple.

Key features

  • High purity (≥97%) suitable for pharmaceutical intermediate use
  • Stable sulfate salt form with excellent storage stability
  • Light yellow crystalline powder, thermally stable up to above 300℃
  • Four reactive amino groups enabling efficient pteridine ring construction
  • Standard packaging (25Kg/Drum) suitable for industrial use

Applications

Key intermediate in the industrial production of methotrexate
Intermediate for antifolate and antineoplastic pharmaceutical synthesis
Precursor for the synthesis of pteridine and pyrimidine derivatives
Used as a precursor for hair colour formulations (oxidative dye coupler)
Applied in fine chemical and heterocyclic compound synthesis
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