Chlorhexidine hydrochloride

Chlorhexidine hydrochloride

CAS 3697-42-5Pharma intermediatesCHC22H32Cl4N10

Specifications

CAS No.
3697-42-5
Molecular formula
C22H32Cl4N10
Molecular weight
578.37
Melting point
111-116°C
Boiling point
Not applicable

Appearance & character

White or almost white crystalline powder, odorless with a bitter taste. It is the dihydrochloride salt of chlorhexidine.

Product overview

Chlorhexidine hydrochloride, also known as chlorhexidine dihydrochloride, is the dihydrochloride salt of chlorhexidine with the chemical formula C22H32Cl4N10 and molecular weight of 578.37 g/mol. It is a surface-active bactericide with strong broad-spectrum antibacterial and bacteriostatic effects against both Gram-positive and Gram-negative bacteria. As a member of the bisbiguanide family, it functions by disrupting bacterial cell membranes. This salt form offers good solubility characteristics for various pharmaceutical and personal care applications, serving as both an active antimicrobial agent and a preservative.

Key features

  • Broad-spectrum antibacterial and bacteriostatic activity
  • Surface-active bactericide
  • Effective against both Gram-positive and Gram-negative bacteria
  • Good solubility characteristics
  • Low toxicity profile
  • Preservative and antimicrobial functions
  • White crystalline powder form
  • Stable under proper storage conditions (2-8°C recommended).

Applications

Pharmaceutical industry
preservative and antimicrobial agent in pharmaceutical formulations
Disinfectant products
surface-active disinfectant for medical and general use
Cosmetics and personal care
preservative controlling bacteria, fungi, and yeast growth
Ophthalmic preparations
preservative in eye drops and ophthalmic solutions
Topical medications
antiseptic in creams, ointments, and lotions
Vaccine development
processing vaccine components for sterility assurance
Microbial culture
selective inhibition in culture media
Industrial applications
antimicrobial agent in various industrial processes.
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