Specifications
- CAS No.
- 7413-34-5
- Melting point
- 212-216℃
- Boiling point
- Not available (decomposes)
Appearance & character
Light yellow to yellow Powder
Product overview
Methotrexate disodium salt is the disodium salt form of methotrexate, an antimetabolite and antifolate agent that inhibits dihydrofolate reductase, thereby preventing the conversion of folic acid into tetrahydrofolate and inhibiting DNA synthesis. It is a light yellow to yellow crystalline powder with improved water solubility, widely used as an antineoplastic API and pharmaceutical intermediate. in water. In acidic solutions, it is colorless, while in basic solutions, it turns pink to purple.
Key features
- High purity (≥98%, HPLC) meeting pharmaceutical grade requirements
- Improved water solubility compared with free methotrexate acid
- Light yellow crystalline powder with well-defined melting point (212-216℃)
- Stable when stored dry, sealed and protected from light (2-8℃)
- Standard packaging suitable for pharmaceutical manufacturing
Applications
- Antineoplastic API for the treatment of certain cancers and autoimmune diseases
- Raw material for pharmaceutical formulations requiring water-soluble methotrexate
- Standard/reference material in pharmaceutical analysis and quality control
- Used in biochemical research as a dihydrofolate reductase inhibitor
- Applied in the production of antifolate pharmaceutical intermediates
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Contact
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- +86 13953312358
- johnson@fengtongchemical.com
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