![N-[4-(Methylamino)benzoyl]-L-glutamic acid zinc salt](https://fengtongchem.com/wp-content/uploads/2026/09/l_p_methylaminobenzoyl_glutamate_zinc-300x300.webp)
N-[4-(Methylamino)benzoyl]-L-glutamic acid zinc salt
Specifications
- CAS No.
- 66104-81-2
- Appearance
- White to off-white Powder
- Melting point
- Not available
- Boiling point
- Not available (decomposes)
Product overview
N-[4-(Methylamino)benzoyl]-L-glutamic acid zinc salt is the zinc salt of N-[4-(methylamino)benzoyl]-L-glutamic acid, a key intermediate in the synthesis of antifolate agents such as methotrexate. It is a white to off-white powder with good stability, and the zinc salt form offers convenient handling and controlled release of the active glutamate moiety in coupling reactions. in water. In acidic solutions, it is colorless, while in basic solutions, it turns pink to purple.
Key features
- Key intermediate for antifolate drug synthesis with consistent quality
- Stable zinc salt form, easy to store, weigh and handle
- White to off-white powder with low impurity profile
- Defined L-configuration ensuring reliable stereochemistry in downstream coupling
- Standard packaging suitable for industrial pharmaceutical production
Applications
- Key intermediate in the synthesis of methotrexate and related antifolate agents
- Raw material for pharmaceutical intermediates in API manufacturing
- Building block for p-aminobenzoylglutamate derivatives in organic synthesis
- Used in pharmaceutical process development and scale-up production
- Applied in fine chemical synthesis requiring L-glutamate backbone units
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