Piperonylic acid

Piperonylic acid

CAS 94-53-1Pharma intermediatesPAC8H6O4

Specifications

CAS No.
94-53-1
Molecular formula
C8H6O4
Molecular weight
166.13
Melting point
229-231°C
Boiling point
324.6°C (sublimes above 210°C)

Appearance & character

White to light yellow crystalline powder or white prismatic/needle-like crystals. It is a benzodioxole derivative with a carboxylic acid group.

Product overview

Piperonylic acid is an organic compound with the chemical formula C8H6O4 and molecular weight of 166.13 g/mol. It is a member of the benzodioxole class, featuring a 1,3-benzodioxole structure substituted with a carboxy group at position 5. This compound is widely used as a research tool in plant physiology studies and as an intermediate in organic synthesis. It exhibits various biological activities including anticancer, antioxidant, and antibacterial properties, making it valuable in pharmaceutical research and development.

Key features

  • White to light yellow crystalline solid
  • Slightly soluble in water, chloroform, cold ethanol, and ether
  • Selective mechanism-based inactivator of trans-cinnamate 4-hydroxylase (C4H)
  • Exhibits anticancer, antioxidant, and antibacterial activities
  • Can sublime at elevated temperatures
  • High purity available (≥98%)
  • Important tool compound for phenylpropanoid pathway studies
  • Stable under normal storage conditions.

Applications

Plant physiology research
selective C4H inactivation tool for phenylpropanoid pathway studies
Pharmaceutical research
investigation of anticancer, antioxidant, and antibacterial properties
Organic synthesis
intermediate for various pharmaceutical and fine chemical compounds
Drug development
precursor for novel therapeutic agents
Agricultural research
plant metabolism and defense mechanism studies
Material science
building block for specialty polymers and materials
Chemical biology
probe for studying enzymatic pathways
Cosmetic ingredients
antioxidant and preservative applications.
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