(S)-(+)-2-Chlorophenylglycine methyl ester (L)-(+)-tartrate

(S)-(+)-2-Chlorophenylglycine methyl ester (L)-(+)-tartrate

(S)-(+)-2-Chlorophenylglycine methyl ester (L)-(+)-tartrate

CAS 141109-15-1Pharma intermediates

Specifications

CAS No.
141109-15-1
Appearance
White to off-white Powder
Melting point
Not available
Boiling point
Not available (decomposes)

Product overview

(S)-(+)-2-Chlorophenylglycine methyl ester (L)-(+)-tartrate is a chiral amino acid ester salt formed with (L)-(+)-tartaric acid. It is a white to off-white crystalline powder with excellent optical purity, and serves as a key chiral building block for the asymmetric synthesis of pharmaceutical actives, especially in the preparation of the chiral side chain of clopidogrel intermediates. in water. In acidic solutions, it is colorless, while in basic solutions, it turns pink to purple.

Key features

  • High optical purity (S)-configuration ensuring reliable chirality transfer
  • Stable tartaric acid salt form, easy to store and handle
  • White crystalline powder with low impurity profile (≥99%)
  • Excellent solubility profile suitable for salt resolution processes
  • Standard packaging (25Kg/Drum) suitable for industrial use

Applications

Key chiral intermediate for the synthesis of clopidogrel intermediates
Building block for chiral 2-chlorophenylglycine derivatives in API synthesis
Raw material for asymmetric synthesis in pharmaceutical R&D and production
Used in resolution and optical purification of racemic phenylglycine esters
Applied in fine chemical synthesis requiring chiral amino acid ester units
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